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Friday, October 4, 2024

What is West Nile Virus? Everything you need to know about Dr. Fauci’s illness

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This week, Dr. Anthony Fauci, former head of the National Institute of Allergy and Infectious Diseases, revealed that he was recovering from West Nile virus. Fauci, 83 was hospitalized for six days and is now recuperating at home.

“A full recovery is expected,” his spokesperson said, according to the Washington Post.

What is West Nile virus (WNV), and how is it spread, treated, diagnosed, and prevented? Read on to learn more.

What is West Nile virus?

Dr. Fauci was hospitalized for West Nile virus. AP

West Nile virus, an infectious disease spread by mosquitoes, first described in 1937, is named for the West Nile district of Uganda where it was discovered. In the US, the virus was first detected in 1999 when a number of human cases were diagnosed in New York.

According to the Centers for Disease Control, West Nile virus is the country’s leading cause of mosquito-borne disease.

In 2023, there were 2,600 cases; the virus sent 1,800 Americans to the hospital and was responsible for 182 deaths. The CDC has confirmed 216 cases so far this year. However, these numbers do not represent the scope of the virus, as many who contract it will not be tested for it.

How is West Nile virus transmitted?

West Nile virus is transmitted via infected mosquitoes. Smith Collection/Gado

West Nile Virus is an illness transmitted via infected mosquitoes, specifically a bite from the Culex mosquito. WNV infects humans, birds, horses, and other mammals. In rare cases, WNV affects dogs and cats.

When bitten, infected birds and horses become viremic, meaning they carry the virus in their blood and can transfer it to mosquitoes that feed off them. Over the summer, that cycle leads to an increase in infected mosquitoes, leading to an increased risk of human infection via mosquito bites. 

Most human infections occur in late summer, peaking in August and September.

Is West Nile virus contagious?

Transmission electron micrograph of West Nile virus particles (red) replicating within the cytoplasm of an infected VERO E6 cell (blue). (Photo by: NIH-NIAID/IMAGE POINT FR/BSIP/Universal Images Group via Getty Images)

In very rare cases, West Nile can be spread through blood transfusion. BSIP/Universal Images Group via Getty Images

According to the CDC, people are considered dead-end hosts for WNV as they do not develop high enough levels of the virus in their bloodstream to pass it on to other mosquitoes who feed on them.

On very rare occasions, the virus is transmitted from person to person by blood transfusion, organ transplant, and from mother to fetus during pregnancy, and from mother to child during delivery or breastfeeding.

In 80 percent of human cases, the disease is asymptomatic, but one in five patients will develop symptoms, and a smaller cohort will require serious medical care.

What are the first signs and symptoms of West Nile virus?

Fever, headache and chills are common symptoms of West Nile

Fever, headache and chills are common symptoms of West Nile. Syda Productions – stock.adobe.com

Symptoms of West Nile present in roughly 20 percent of people infected and typically appear between three and fourteen days after being bitten. Symptoms include:

  • Fever
  • Chills
  • Headache
  • Body aches
  • Rash
  • Vomiting and diarrhea

Is West Nile virus deadly?

West Nile Virus

West Nile virus is the leading cause of mosquito-borne disease in the U.S. Universal Images Group via Getty Images

In rare cases, about 1 in 150, serious complications and neurological symptoms, including meningitis and paralysis, have been reported in patients with WNV. Roughly one in ten people who develop serious symptoms die from the infection.

Risk increases with age, and those over 60, like Fauci, are most vulnerable. Other compromised populations include those with cancer, diabetes, hypertension, kidney disease, or organ transplant recipients.

Of the 216 WNV cases reported this year, 142 involved neuroinvasive disease, the most serious form of WNV fever.

What is the treatment for West Nile virus?

The best course of action is infection prevention.

The best course of action is infection prevention. Getty Images

There is no specific treatment or vaccine for West Nile virus. The best course of action is to prevent infection. The CDC recommends the following precautions.

  • Use DEET-containing mosquito repellant. 
  • Dress in loose-fitting clothing that covers both arms and legs
  • Use air conditioning when possible, or ensure that open windows and doors have screens.
  • Empty standing water from common items around the exteriors of houses, such as bird baths, flower pots, and toys, where mosquitoes can lay their eggs.

West Nile in NYC

Culex pipien mosquito specimen at the Field Museum, a carrier of the West Nile virus

Culex mosquito specimen at the Field Museum, a carrier of the West Nile virus TNS

As of last month, mosquitoes with West Nile virus have been confirmed in all five boroughs of New York City, according to city health officials.

In October 2021, West Nile virus cases in NYC tripled during one of the worst mosquito seasons to hit the northeast. 

Only 18 people in the city have been killed by the disease since the first known case.

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